7 Most Powerful Prayers Throughout History

Pray without ceasing.
1 Thessalonians 5:17

7 Most Powerful Prayers Throughout History

Contrary to some secular proclamations, there are indeed certain elements that help to maximize prayer’s power and efficacy. Being in a state of grace and praying with great faith, humility and gratitude are a few of those attributes known world over. Another important element is to say the right kind of prayer. Praying with God’s Word, for example, is highly beneficial and effective. And while it is true that our Heavenly Father can hear even the faintest of a whispered prayer, there exists strong historic proof that certain prayers are answered more frequently than others; thus, giving way to bigger blessings and breakthroughs.

In this article, we are going to focus on seven prayers in particular that, for various reasons, seem to hold much power in Heaven. As you pray these 7 Most Powerful Prayers Throughout History, be sure to pray them with unwavering faith. Believe in their power. As Jesus said, “According to your faith let it be done unto you” (Matt. 9:29). Moreover, try to be especially attentive to the promptings of the Holy Spirit. Listen intently for His voice. Remember, praying to God has two equal parts: speaking and listening. For those of you looking to enhance your prayer-life even further, add fasting to this routine.

7 Most Powerful Prayers Throughout History

Our Father

This is the quintessential Christian prayer given to us by Jesus Christ Himself (Matt. 6:9-13). It is often prayed as an “all occasion” prayer; one that touches on all of life’s moving parts. Among other things, the Our Father Prayer acknowledges God’s greatness, invites His divine will into our lives, petitions Him for our needs, and requests pardon for our sins as we, too, pledge to forgive those who have (and will) sin against us.


Our Father, Who art in Heaven, hallowed be Thy name;
Thy Kingdom come, Thy will be done, on earth as it is in Heaven.
Give us this day our daily bread;
and forgive us our trespasses as we forgive those who trespass against us; and lead us not into temptation, but deliver us from evil.

(This prayer is often followed by 3 Hail Mary Prayers. If said alone, say throughout the day as often as needed.)

Jesus at Gethsemane

This prayer, because of its short length, is perhaps one of the most simple to recite. However, the Jesus of Gethsemane Prayer is one of the most profound prayers still recited today. Prayed by Jesus Himself, it demonstrates how we must accept God’s will for our lives, even when we do not understand it or like it. By accepting and obeying the will of the Lord, our lives will be transformed for the better. If the day has come when the cup has come to you, arm up in faith, having the courage to answer “Lord, Thy will be done” by reciting this prayer (Mark 14:36; Luke 22:42).


Father, if You are willing, take this cup away from me.
Nevertheless, let Your will be done, not mine.

(repeat 3 times as a sequence as often as needed throughout the day)

Hail Mary

Mary, the Mother of our Lord, is an incredibly powerful intercessor — demonstrated not only throughout Scripture (i.e., the Wedding at Cana) but also throughout history (I, too, have personally witnessed her intercession in my own life). The testimonies of people whose lives have been transformed by her healing intercession are both spectacular and too innumerable to recount for our purposes here. That said, this remarkably simple prayer which has but a few elements, all of which are taken from Holy Scripture, praises Mary as Jesus’ blessed Mother and humbly implores her intercession. It is a shorter prayer which makes it easier to memorize and to pray in times of need. Additionally, praying the Hail Mary in its entirety with the Rosary devotion intensifies its power. The full Rosary Prayer is arguably the worlds most powerful devotion today. With innumerable miracles and conversions to its credit, the Hail Mary is an extraordinary — and extraordinarily powerful — prayer.


Hail Mary full of Grace,
the Lord is with thee.
Blessed are thou among women,
and blessed is the fruit of thy womb Jesus.
Holy Mary, Mother of God, pray for us sinners
now and at the hour of our death

(Repeat 3 times in succession. Repeat as often as necessary throughout the day and when you are in need of intercessory aid from Heaven)

Prayer to St. Michael the Archangel

There are few words the devil hates more to hear (aside from the Rosary) then this prayer to his victor, the Archangel Michael. Not only does satan and the Archangel have a battle-filled past (with another on the way — *See Rev. 12:7-10), St. Michael the Archangel is the defender of all God’s faithful … and his sword is swift and keen. When confronted with evil, this prayer invokes St. Michael’s incredible protection and mighty intercession into our lives.


Holy Michael, the Archangel,
defend us in battle.
Be our safeguard against the wickedness and snares of the devil.
May God rebuke him, we humbly pray;
and do you, O Prince of the Heavenly host,
by the power of God,
cast into hell Satan and all the evil spirits who wander through the world seeking the ruin of [all our] souls.

(Pray in the morning and any other time during the day you are in need of protection against the wiles and threats of the devil)

David’s Prayer for Deliverance

Pursued by his own brother, King David prayed for God to deliver him from his enemies. It seems most of us have or have had enemies who, for whatever reason (and perhaps with the help and influence of evil forces), seek to harm us in one way or another. When faced with such opposition, just as the psalmist did, we should not hesitate to cry out for divine protection from our Lord.


Lord, how many are my foes!
    How many rise up against me!
Many say of me,
    ‘God will not deliver him.’
But You, Lord, are a shield around me,
    my glory, the One Who lifts my head high.
I call out to You, Lord,
  and You answer me from Your Holy mountain.
I lie down and sleep;
    and I wake again, because You sustain me.
I will not fear though tens of thousands
    assail me on every side.
Arise, Lord!
    Deliver me, my God!
Strike all my enemies;
    break the wicked.
From You, Lord, comes my deliverance.
    May Your blessing be on all Your people.

(Adapted from Psalm 3)

The Prayer of Jabez

This is a life-changing prayer. It is often overlooked because of its short length and because it is buried deep in Old Testament genealogy. It was written by Ezra, the author of 1 Chronicles. In short, this prayer is a petition to God in which Ezra asks the Lord for a blessing of abundance as well as divine protection. Two blessings we are all in need of today!


Oh that You would bless me indeed, Lord,
and enlarge my border,
and that Your hand might be with me,
and that You would keep me from harm
that it may not pain me.

And God granted him what he requested.

(Repeat 3 times in a sequence as often as necessary)
*Adapted from 1 Chronicles 4:10

Jonah’s Prayer for Salvation

We will all face distressing times in life, as did those who walked before us. Jonah found himself in the belly of a whale! From this dark place of despair and hopelessness, he cried out to the Lord for salvation. He knew that only his Savior could rescue him, and so it is with us today. O how we often find ourselves in the belly of the beast! But in the midst of uncertainty, and because of our Lord’s great mercy, we are able to cry out to Him knowing that He is more than able and more than mighty to save us.


For You, Lord, had cast me into the deep,
into the heart of the seas,
and the current engulfed me.
All Your breakers and billows passed over me.
So I said, ‘I have been expelled from Your sight.
Nevertheless I will look again toward Your Holy Temple.’

Water encompassed me to the point of death.
The great deep engulfed me,
weeds were wrapped around my head.
I descended to the roots of the mountains.
The earth with its bars was around me forever.
But You have brought up my life from the pit, O Lord my God!
While I was fainting away,
I remembered the Lord,
and my prayer came to You,
into Your Holy Temple.
Those who regard vain idols
forsake their faithfulness;
But I will sacrifice to You, Lord,
with the voice of thanksgiving.
That which I have vowed I will pay.
Salvation is from the Lord.

(Adapted from Jonah 2:3-9)

These prayers have been proven to transform lives and change entire Nations. As you pray, consider the power each one of these prayers has and the changes they can make in your own life. Make them a part of your daily prayer routine and, with faith, watch what happens.

See Also:
Most Powerful Psalm of Protection: Psalm 91
19 Best Psalms for Healing
7 Powerful Psalms for a Financial Breakthrough
Powerful Prayer for a Miracle

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